Medical oxygen generators: Cost-Effective oxygen production for modern healthcare

Medical oxygen generators

In healthcare settings, particularly in hospitals, medical oxygen serves as a critical lifeline. High-purity medical oxygen is essential for a range of treatments, including respiratory therapy, anesthesia, and life support. Among the methods of oxygen supply, oxygen generators, especially the Pressure Swing Adsorption (PSA) oxygen generators, have emerged as indispensable technologies. In today’s healthcare settings, medical oxygen is primarily supplied through three main methods: PSA oxygen generators, oxygen concentrators, and through bulk oxygen delivery. Historically, hospitals and healthcare facilities, especially in upper-middle- and high-income economies, have depended on the practice of storing and transporting oxygen, or the method known as bulk oxygen delivery. These methods have often proved inadequate in meeting the increasing healthcare demands, a fact that became particularly evident during the COVID-19 pandemic. In contrast, low- and middle-income economies frequently struggle with the challenges of limited infrastructure and unreliable supply chains.

Furthermore, it has become evident that oxygen concentrators, as one the most widespread solution in low- and middle-income economies, are the least effective solution, particularly for critical patients. For example, one unit produces oxygen for one patient which often fall into disrepair due to the cost and complexities of maintaining them (Ref. PATH and WHO).

Oxygen delivery systems like PSA oxygen gas generators, on the other hand have become more pronounced, as they deliver stable on continuous supply of oxygen. Weighing the distinct requirements and constraints of healthcare settings, the following sections details the three primary methods of oxygen supply, their advantages, and disadvantages. 

As contemporarily stands, there are three main ways of medical oxygen supply, which include PSA oxygen generators, oxygen concentrators, and bulk oxygen delivery. Each method offers their unique advantages and disadvantages. PSA oxygen generators provide on-site production, oxygen concentrators offer portability, while bulk oxygen delivery is ideal for high-demand settings. These methods form the backbone of oxygen supply in global healthcare.

PSA Onsite oxygen generators (PSA Plants)

PSA oxygen generators, also known as PSA plants, are standalone oxygen generation systems designed to produce oxygen for multiple patients simultaneously. They work by using a flow and compression process to extract oxygen from the air. PSA plants are commonly utilized in larger healthcare facilities and hospitals. While they require a significant upfront capital investment, they offer scalability and are cost-effective in delivering a consistent oxygen supply.

Small OXYMAT PSA Oxygen plant.

Advantages of onsite oxygen systemsDisadvantages of onsite oxygen systems
Stable and continuous supplyHigher initial capital investment
Efficient for high oxygen demandEnergy and infrastructure requirements
Cost-efficient over timeMaintenance (trained personnel)
Reduced dependence on suppliers 
No need for cylinder handling 
Lower ongoing oxygen costs 
Reduced transportation risks 
Physical footprint 
Customizable oxygen concentrations 
Filling cylinders and tanks if needed 

Oxygen concentrators

Oxygen concentrators are simple devices used to extract oxygen from ambient air. They operate by removing nitrogen from the air, resulting in a concentrated oxygen supply that can be delivered to patients through nasal cannulas or masks. This method is often preferred in healthcare facilities with limited resources, particularly in low- and middle-income economies. However, apart from being advantageous in some healthcare settings, they have their noticeable limitations. As such they are only used for non-critical patients, they have short life span and have a limited oxygen purity rate, among others.   

Bulk oxygen supply

Bulk oxygen supply and its storages involve the production of highly purified liquid oxygen through a process known as cryogenic fractional distillation. Liquid oxygen is stored in bulk tanks and can be distributed in various forms, such as converting it into gas and storing it in cylinders and distributing it through hospital pipelines.

Advantages of bulk oxygen storage systemsDisadvantages of bulk oxygen storage systems
Stable and continuous supply of oxygenHigher initial capital investment
Suitable for larger healthcare facilitiesRequires well-established operational model
Efficient for high oxygen demandSteady demand needed for cost-effectiveness
Can be used in high-income countriesRequires reliable transportation infrastructure
 Requires specialized storage and handling
 Complex installation
 Large physical footprint
 Safety considerations (high flammability)
 Cost of cryogenic infrastructure
 Environmental impact (transport and maintenance)
 Risk of supply disruptions
 Oxygen price fluctuations
 Gasification (Safety risks) 

The three methods highlighted above indicate that medical oxygen supply in healthcare settings faces significant challenges, and as sector does not seem to adequately be prepared for future developments. Before selecting the appropriate oxygen supply method, it is necessary to thoroughly understand the whole ecosystem. This includes addressing the increasing demands due to a growing and aging population, as well as the needs of remote or under-resourced areas.

In this context, medical oxygen generators, stand out as a most viable solution for long-term and critical needs. Their capability to deliver a stable and continuous on-site oxygen makes them fundamental in building a sustainable healthcare. As in bulk delivery, they are efficient for both high and low oxygen demand. Their dependence on a stable electricity supply, on the other hand, can pose difficulties, especially in regions with unstable electric power resources. However, incorporating renewable energy sources such as solar and wind power into their settings, can offer a solution to power-related challenges.

Additionally, what makes PSA medical oxygen generators a more suitable choice, especially for hospitals and healthcare facilities that depend on oxygen bulk delivery and cylinders, is the fact that they can also be used to store the generated oxygen in cylinders and tanks. They can easily be incorporate them into already existing oxygen distribution infrastructure.    

OXYMAT’s PSA oxygen generators stand out for their ability to deliver stable and continuous on-site supply of medical oxygen. OXYMAT Two-column, known also as the Two-tower generators are known for their quality and reliability. Their robust build up has made them the preferred choice for many healthcare facilities and diverse healthcare environments in more than 150 countries. Depending on the healthcare facility’s settings, needs, and location, OXYMAT offers solutions either as standalone onsite oxygen generators or as turnkey solutions, equipped with service offerings.

Medical PSA oxygen generator

OXYMAT PSA systems consist of several components including a compressed air system, which encompasses an air compressor, refrigeration dryer, air receiver, and filters. Additionally, the turnkey solution includes a PSA skid, an oxygen receiver, and optionally, an oxygen booster and filling station, as well as a container or a frame-built solution if required. The capacity of the generators ranges from 2 to 189 Nm³/h, with purities reaching up to 95%.

Furthermore, key features of the OXYMAT oxygen generators include low energy consumption as low as 1.0 kW/m³ of oxygen, and low CO2 emissions. OXYMAT PSA oxygen generators are certified with various international approvals, including ISO 9001, ISO 13485(en), ISO 14001, and several others, ensuring compliance with global standards in healthcare and environmental management.

Download Oxymat´s medical oxygen brochure


Medical oxygen is critical in healthcare, with PSA oxygen generators, oxygen concentrators, and bulk oxygen delivery being the primary supply methods. Each method has its pros and cons, however PSA oxygen generators emerge as a highly effective solution. They offer stable, continuous on-site oxygen production, suitable for a wide range of healthcare settings. Despite a higher initial cost and infrastructure needs, they are cost-effective in the long run, as they reduce dependency on external suppliers and are unaffected by oxygen price fluctuations. One challenge that comes with installing a PSA oxygen plant, particularly in the remote areas, is the requirement for stable electric power. However, incorporating renewable sources of energy in their settings can also eliminate these challenges.

Oxygen concentrators are more suited for non-critical patients and those in resource-limited settings. While they are simple to use, their limitations in flow, maintenance and oxygen purity, rates, maintenance etc. makes them less viable as a solution.

Bulk oxygen supply, on the other hand, is ideal for high-demand environments, yet the solution presents its own set of challenges, including transportation infrastructure, high initial investment risks and a significant environmental footprint.

OXYMAT’s PSA generators stand out with their low energy consumption, adherence to international standards, and global application, making them a preferred choice in many modern healthcare facilities for both high and low oxygen demands.

Do you need a hand?

You are in the right place.